2023 365 Data Science. 370. She is also a popular YouTuber with over 60k subscribers. In product development, we do lots of opportunity sizing to decide which features to build and what opportunities to invest in. Ruiz-Redondo, A. et al. 2022 Weird Science Plus - All Rights Reserved. Tina Huang, a data scientist currently working at a FAANG (Facebook, Amazon, Apple, Netflix, and Google Alphabet) company. Total students. Villalba-Mouco, V. et al. 276, 107319 (2022). PubMed Paradis, E., Claude, J. By contrast, the Goyet Q116-1 genetic profile gave rise to the newly described Fournol cluster identified in Gravettian-associated individuals from western and southwestern Europe. The colours correspond to the grouping of tested populations, dots refer to the f4-values and the dark and light error bars to 1*SE and 3*SE estimated from 5 cM block jackknife, respectively. Fourth, we extend the finding of a large-scale genetic turnover as early as 14ka in central and western European hunter-gatherers associated with multiple techno-complexesFedermesser, Azilian and other Final Palaeolithic groups4despite considerable technological continuity with the preceding late Magdalenian. Proc. I help students become independent data scientists who are not just good at data analysis, but are also able to think about their own learning and the world around them. The emergence of hunter-gatherer pottery in the Urals and West Siberia: new dating and stable isotope evidence. Biotechniques 59, 8793 (2015). (black) or 3s.e.m. The ancestry found in individuals associated with the preceding Aurignacian culture from central Europe (GoyetQ116-1ancestry) gave rise to Gravettian-associated individuals from western and southwestern Europe. Also if you want to see some cat pics. tina huang data science Explained in Instagram Photos. performed mortuary practices analyses. I'm a data scientist and youtuber. Article Within Sicily, the 14ka Oriente C individual shows higher affinity with the much younger but geographically closer 10ka Uzzo group30 (n=2) than with the almost contemporaneous San Teodoro 2 individual from eastern Sicily. Showcase your skills and bolster your data science credentials. Front. Therefore, contrary to previous suggestions34, this demonstrates that the post-LGM diffusion of the Magdalenian was indeed associated with northward and northeastward population expansions from western Europe35. Rohland, N. & Hofreiter, M. Ancient DNA extraction from bones and teeth. Protoc. Charlton, S. et al. Admixture events were dated using the ancestry covariance pattern-based DATES 753 program105, with a bin size of 0.1 cM for covariance calculation and the start of exponential fitting at d0.5cM. and H.F. produced a subset of the radiocarbon dates. Shes the founder of Coding Black Females, a nonprofit with the aim to provide opportunities for Black female developers to develop themselves, meet familiar faces, network, receive support, and build relationships through having regular meetups., Check out the Coding Black Females website. Surprisingly, the research team found that populations from different regions associated with the Gravettian culture, which was widespread across the European continent between 32,000 and 24,000 years ago, were not closely related to each other. Djindjian, F. Territories and economies of hunter-gatherer groups during the last glacial maximum in Europe. University Universit Chouaib Doukkali; . The key areas to focus on when getting started in data science [6:01] Tina's five steps to consistently doing anything [11:55] Tina's day-to-day life as a data scientist at one of the world's largest tech companies [20:02] How Tina's computer science background helps her work [26:20] Traditional banking culture vs big tech [32:12] These authors contributed equally: Cosimo Posth, He Yu, Archaeo- and Palaeogenetics, Institute for Archaeological Sciences, Department of Geosciences, University of Tbingen, Tbingen, Germany, Senckenberg Centre for Human Evolution and Palaeoenvironment at the University of Tbingen, Tbingen, Germany, Cosimo Posth,Dorothe G. Drucker,Herv Bocherens,Christoph Wiing,Nicholas J. Conard&Katerina Harvati, Department of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany, Cosimo Posth,He Yu,Ayshin Ghalichi,Hlne Rougier,Yilei Huang,Harald Ringbauer,Adam B. Rohrlach,Kathrin Ngele,Vanessa Villalba-Mouco,Rita Radzeviciute,Tiago Ferraz,Alexander Stoessel,Rezeda Tukhbatova,Wolfgang Haak&Johannes Krause, State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China, Department of Anthropology, California State University Northridge, Northridge, CA, USA, Universit de Bordeaux, CNRS, MC, PACEA UMR 5199, Pessac, France, Isabelle Crevecoeur,Andr Morala,Stphane Madelaine,Priscilla Bayle,Bruno Maureille,Jean-Guillaume Bordes&Mona Le Luyer, School of Mathematical Sciences, University of Adelaide, Adelaide, South Australia, Australia, Instituto Universitario de Investigacin en Ciencias Ambientales de Aragn, IUCA-Aragosaurus, Zaragoza, Spain, Department of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, Germany, Institute of Zoology and Evolutionary Research, University of Jena, Jena, Germany, Center of Excellence Archaeometry, Kazan Federal University, Kazan, Russia, Department of Biology, University of Florence, Florence, Italy, Martina Lari,Alessandra Modi&Stefania Vai, Estonian Biocentre, Institute of Genomics, University of Tartu, Tartu, Estonia, Tina Saupe,Christiana L. Scheib&Luca Pagani, St Johns College, University of Cambridge, Cambridge, UK, Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Palermo, Italy, Department of Biology, University of Padova, Padova, Italy, Department of Chemistry G. Ciamician, Alma Mater Studiorum, University of Bologna, Bologna, Italy, Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany, UMR 8068 CNRS, TEMPSTechnologie et Ethnologie des Mondes Prhistoriques, Nanterre Cedex, France, Laurent Klaric,Olivier Bignon-Lau,Grgory Debout,Michel Orliac,Pierre Bodu,Bndicte Souffi&Frdrique Valentin, Muse National de Prhistoire, Les Eyzies de Tayac, France, UMR 5140 CNRS, Archologie des Socits Mditerranennes, Universit Paul-Valry, Montpellier, France, UMR 7194, Histoire Naturelle de lHomme Prhistorique (HNHP), Dpartement Homme et Environnement, Musum National dHistoire Naturelle, CNRS, UPVD, Paris, France, Association APRAGE (Approches pluridisciplinaires de recherche archologique du Grand-Est), Besanon, France, Skeletal Biology Research Centre, School of Anthropology and Conservation, University of Kent, Canterbury, UK, Dipartimento di Scienze Fisiche, della Terra e dellAmbiente, U.R. Bioinformatics 29, 16821684 (2013). Korneliussen, T. S., Albrechtsen, A. 5). 8). Radiocarbon 55, 163177 (2013). Fifth, the Oberkassel ancestry in western and central Europe and the Sidelkino ancestry in eastern Europe remained largely isolated for almost 6,000 years until genetic interactions were first observedaround 8ka in northeastern Germany, possibly associated with cultural exchanges along the Baltics49 and around 7.5ka in the upper Volga region, possibly linked to the spread of pottery in the region50. Hi! Curr. 26, 827833 (2016). Science 365, eaat7487 (2019). Sci. Both of these books focus on the science and math behind data mining. Instead, in southern Europe, a distinct hunter-gatherer genetic profile was found as early as 17ka in individuals associated with the Epigravettian culture15 (2412ka, from the Italian peninsula to the southeastern European Plain across the Balkans). 1 MtDNA and Y-chromosome phylogenies. We love meeting interesting people and making new friends. Jones, E. R. et al. Required fields are marked *. . The observation that post-14ka individuals from western and central Europe andalso from Britain41 carry a homogeneous genetic makeup instead of displaying repeated local admixtures with GoyetQ2 ancestry implies that the Oberkassel-ancestry profile was already largely formed before its dispersal. 4, 11 (2007). F4-statistics also show that the approximately8.2ka Yuzhniy Oleniy Ostrov group from Karelia in western Russia formed by 19 genomes has comparable or lower affinity to Villabruna ancestry than all the other EHG groups (Supplementary Data 2.K). The lsqproject: YES parameter was used to minimize the effect of missing data in ancient individuals. As a general rule of thumb, we start from the simplest issue and gradually increase in complexity. The horizontal dashed line marks the boundary between Late Pleistocene and Holocene. This is . Unlike setting up a Premium subscription to our platform, for which you would be billed monthly or annually, acquiring individual courses requires a one-time payment only. Libraries showing a mitochondrial or nuclear contamination rate over 10% were considered substantially contaminated whereas those between 5 and 10% were considered marginally contaminated and were treated differently (details are provided in Supplementary Information, section3). Hi, my name is Tina and I'm a data scientist at a FAANG company. Tina is proud she taught herself SQL from scratch in 11 days to pass her FAANG SQL interview. Her first stepping stone into data science was being a research assistant in Bioinformatics. Data warehousing is a field where you often have to deal with a lot of raw data. Article The grouping of Epigravettian-associated populations is shown with the same colour in a. Commun. She has been working for the data sciences industry since 2014. Radiocarbon 62, 725757 (2020). Science 358, 659662 (2017). However, its formation, diffusion and interaction with contemporaneous hunter-gatherers from eastern Europe and their interplay with later expansions of Neolithic farmers from southeastern Europe are not well characterized. Highly Influential Citations 3. Kozowski, J. K. The origin of the Gravettian. Her channel is about data science, transitioning into computer science and software engineering. Science 363, 12301234 (2019). Well be back on Friday so, if youre not already, get subscribed to the Brandwatch Bulletin right away. Now we have Areej AbuAli, an SEO manager and the founder of Women in Tech SEO. Rohrlach, A. Currently use of the word 'vape' now means "to inhale and exhale the vapor produced by an . Our limited-time offer covers individual course purchases only. K.H. Tina started her YouTube channel in 2020. My main tasks: Modeling and developing the data structures and processes to optimize the loads of information, discovering insights and creating and maintaining reports. Prfer, K. et al. Dashed lines show the frequencies estimated for the indicatedpresent-day 1000 GenomesProject populations (CEU, Utah residents of northern and westernEuropean ancestry; GBR, British; IBS, Spanish;TSI,Tuscan)37. Reads with a mapping quality below 30 were then filtered with samtools, and the consensus sequences were generated by Schmutzi69. iScience 25, 104244 (2022). PubMed Central After the LGM, a genetic component distantly linked to the Goyet Q116-1 individual from Belgiumdated to 35 kanamed GoyetQ2 ancestry(hereafter, GoyetQ2 cluster or ancestry)reappeared in individuals from southwestern and central Europe associated with the Magdalenian culture (1914ka from Iberia to eastern Europe across central Europe) and in an admixed form in subsequent Final Palaeolithic and Mesolithic hunter-gatherers4,14, but the geographic extension of this ancestry is still unclear. My name is Tina and I'm a data scientist and YouTuber. Teaching Assistant. This means that you have to set up the database tables to represent the data (which can be done by using the right database design patterns) and then run some SQL queries to extract the data that you need. This channel is about data science, learning, and productivity. Rivollat, M. et al. Int. Weissensteiner, H. et al. I Agree, Brandwatch Bulletin #41: 7 Women in Tech You ShouldKnow. Sci. Further palaeogenomic studies on Upper Palaeolithic individuals from the Balkans will be essential for understanding whether southeastern Europe represents the source of the Villabruna ancestry and a climatic refugium for human populations during the LGM. Billed once. A subset of samples (GER002 and GER003) were pre-treated with a washing step to reduce surface contamination54. Each aDNA library was double indexed60 in 14 parallel 100l reactions using PfuTurbo DNA Polymerase (Agilent). Biol. After another MinElute purification, the product was quantified using the Agilent 2100 Bioanalyzer DNA 1000 chip. The authors declare no competing interests. Compared with the genetic diversity observed among all analysed Gravettian-associated groups, Epigravettian-associated individuals show significantly lower amounts of genetic diversity (two-tailed t-test, P<0.001) (Fig. Photo by Sara Kurfe on Unsplash 1. 9) and testing the relative affinity among them using f4-statistics in the form f4(Mbuti, Epigravettian A; Epigravettian B, Epigravettian C) (Supplementary Data 2.E). Tinas authentic and engaging delivery style allows her to create original content on topics like how to be more productive, how to learn more efficiently, how to land a job in data science, and more. On the basis of PCA and outgroup f3-statistics, the Neolithic Tutkaul 1 individual from Tajikistan is closely related to Upper Palaeolithic individuals from south-central Siberia (Afontova Gora 3 (AG3) and Malta 1), and roughly contemporaneous West Siberian hunter-gatherers (Tyumen and Sosnoviy), both carrying high proportions of ANE ancestry45 (Fig. Moreover, we reveal a north-to-south decrease in genetic diversity among the Epigravettian-associated groups, with the highest PMR and heterozygosity values found in northern Italian individuals (group 1), intermediate in western and central Italian individuals (group 2) and the lowest in Sicilian individuals (group 3) (Fig. S. Shnaider received support from theRussian Science Foundation (no. 581582, 128163 (2021). Details on individuals involved in the analysis, read counts processing and allele frequency computation are provided in the Supplementary Information, section12 and Supplementary Data 1.J and 3.G. 1a, and the y-axes report time in thousand years before present (kBP). b, Population diversity shown by PMR between individuals in different groups. The PCA was calculated with 1379 individuals from 87 western Eurasian modern populations on the 1240k_HO dataset, which was intersected between the 1240k and Human Origins datasets (Supplementary Data 1.K). As previously hinted37, we find a large frequency variation in alleles related to skin and eye pigmentation among post-LGM hunter-gatherer groups. Fab Business Solutionsis a ProfessionalNewsPlatform. W jednej z historii misiaczki za rad pewnej wydry zamieszkuj w tajemniczym . No need to do it alone our community of learners and instructors is there for you. . & Posth, C. Latest trends in archaeogenetic research of west Eurasians. The sample size of individualpairsincluded in each groupis reported in SupplementaryData 3.A. I hold a Bachelor's degree at the University of Toronto where I studied pharmacology. 14, evac045 (2022). For ds_halfUDG libraries, we called genotypes on all targeted sites from 2bp-masked bam files; for ds_nonUDG libraries, we called genotypes on transversion sites only; for ss_nonUDG libraries, we called genotypes with single-strand mode, which ignores forward reads at C/T polymorphisms and reverse reads at G/A polymorphisms. Evol. 16, 224 (2015). Along with pushing for more accessibility, she also creates content around working in the tech industry, the challenges that come with it, and career advice. Tina Huang. Nature thanks Marta Mirazn Lahr, Ludovic Orlando and the other, anonymous, reviewer(s) for their contribution to the peer review of this work. L. Sineo, M.L. Wonderful course so far Tina. In panel b, the colour code does not imply archaeological similarities. A phylogeographic reconstruction of different lineages carrying this ancestry further suggests its entry point into northeastern Italy from the Balkans followed by a north-to-south expansion into the Italian peninsula alongside a population decline through sequential bottlenecks. Seguin-Orlando, A. et al. The purified products were amplified in multiple 100l reactions using Herculase II Fusion DNA Polymerase (Agilent) following the manufacturers specifications with 0.3M of the IS5/IS6 primers. Ecologizr. A genome sequence from a modern human skull over 45,000 years old from Zlat k in Czechia. Provided by the Springer Nature SharedIt content-sharing initiative. I hold a Bachelor's degree at the University of Toronto where I studied pharmacology. Olalde, I. et al. This might also explain the genetic uniformity of the Oberkassel cluster across large parts of western Eurasia but genomic data from between 15 and 14ka is needed to understand the exact dynamics of this turnover. However, published Gravettian-associated genomes originate from central and southern Europe, leaving the genetic profile of Gravettian-associated humangroups from western and southwestern Europe undescribed. Liet. By using our site you agree toour The newly defined Fournol cluster is closely related to Aurignacian-associated individuals from Belgium dated to 35ka (Goyet Q116-1 and the newly reported Goyet Q376-3 individual). The f3-statistics were calculated with qp3Pop 435 in ADMIXTOOLS 5.1 package103. Meyer, M. & Kircher, M. Illumina sequencing library preparation for highly multiplexed target capture and sequencing. National Science Council feb. 2009 - feb. 2009 1 maand. Notably, the Fournol ancestry provides a better proxy than Goyet Q116-1 for the genetic component found in the GoyetQ2 cluster and in El Mirn (Supplementary Data 2.H). Natl Acad. Freshwater radiocarbon reservoir effects at the burial ground of Minino, Northwest Russia. We only plotted groups with more than two individuals and, for this reason, individuals from the GoyetQ116-1 cluster are included here into the Fournol cluster. 6 Reasons We Just Cant Stop. USA 116, 16391644 (2019). DNA analysis of an early modern human from Tianyuan Cave, China. We thus modelled individuals belonging to the GoyetQ2 cluster and El Mirn as a mixture between the Fournol 85 and Arene Candide 16 genomes as proxies to represent the Fournol and Villabruna ancestries, respectively, in Magdalenian-associated groups (Fig. We then attempted to model 250 published and newly reported hunter-gatherers dated to 145ka using qpAdm as a mixture of Oberkassel, Sidelkino, GoyetQ2 ancestries, and an ancestry maximized in Anatolian Neolithic farmers (ANF), as a considerable portion of the sequenced hunter-gatherer genomes date after around 8ka, when ANF ancestry started spreading across Europe. Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. 211 and Supplementary Table 1). 7 Admixture dates between Oberkassel/Villabruna and ANE ancestries in the oldest individuals from the Sidelkino cluster. One of the best-known and most liked personalities in the data community, Tina is a successful YouTuber and works with one of the FAANG companies. You are using a browser version with limited support for CSS. Write a sharp and effective resume in minutes and get noticed by employers. Bronk Ramsey, C. Bayesian analysis of radiocarbon dates. 6, 8912 (2015). We then removed samples with less than 0.04X coverage (calculated on the mappable, non-recombining region of the Y chromosome98) to avoid arbitrarily placing low-coverage samples at the root of major haplogroups. Nucleic Acids Res. Paleogenomic evidence for multi-generational mixing between Neolithic farmers and Mesolithic hunter-gatherers in the Lower Danube Basin. W jednej z historii misiaczki za rad pewnej wydry zamieszkuj w tajemniczym domostwie. 1) we used MUSCLE (-maxiters 2)96 to create a multiple genome alignment of previously published sequences and newly reported mtDNA consensus sequences with q20 according to defined thresholds (minimum average coverage >5-fold, contamination estimate <20%, HaploGrep2 haplogroup assignment consistent with manual assignment). Google Scholar. Herein, methane is upgraded through the photocatalytic oxidative coupling of methane (OCM) over a ternary Ag-AgBr/TiO 2 catalyst in a pressurized flow reactor. Her YouTube channel is dedicated to data and computer science, including how to educate yourself in these topics. Her motto to live by is "Always minimize effort and maximize outcome!". Therefore,most of the ancestry found in these post-LGM individuals probably traced back to Gravettian-associated groups from western and southwestern Europe.
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